Vinnie Pasquantino headlines Friday night's top MLB prop picks.
Today's MLB props narrative: I love tonight's matchup for Pasquantino against Philadelphia Phillies right-hander Walker Buehler. Pasquantino is swinging a hot stick, leading to a pair of plus-money plays on him.
Check out my top MLB prop bets for Sept. 12, featuring predictions on Jackson Holliday and Mookie Betts.
BET FINDER: Search & Bet!
MLB prop bets
Best bet: Pasquantino over 1.5 bases (+112) & 1+ RBI (+140)
Pasquantino will have the platoon advantage at a good hitter’s park against a pitcher who has struggled tremendously and was recently designated for assignment. There’s a lot to like here.
As the No. 3 hitter, Pasquantino will, in all likelihood, hit behind Mike Yastrzemski and Bobby Witt Jr.
Yastrzemski thrives with a platoon advantage (.363 on-base percentage vs. LHP), and Witt is a hitting machine who has gotten on base at least once in 84% of his games in the second half.
I like Pasquantino to have a shot at driving them in against Buehler, who put up a 5.45 ERA and 1.56 WHIP in 23 games before getting cut by the Boston Red Sox.
The Kansas City Royals first baseman has pop, too, easily setting a career-high with 30 homers and counting, and he’s one of nine players with 100-plus RBI this season.
- Pasquantino is batting .306/.350/.528 in September. He slugged .550+ in both July and August.
- His OPS is more than 200 points greater vs. right-handers, and he’s blasted 25 of his bombs against RHPs.
- Left-handed batters are hitting .317 with an .877 OPS vs. Buehler, and they torched him last year, too.
I see potential for a monster game at Citizens Bank Park.
Key stat: Pasquantino ranks 11th in second-half ISO.
Best MLB picks
Betts over 1.5 bases (+128): I'm riding the Mookie train. I've played this all week, and this is the best price yet.
There's reason for that: Betts and the Los Angeles Dodgers run into a hot San Francisco Giants team at their pitcher-friendly venue, facing Justin Verlander, who has been throwing great.
On top of that, the Giants' bullpen has been strong, and Verlander has owned Betts.
Betts has three hits in 32 career plate appearances vs. Verlander (.100/.156.133). But he has only struck out three times and is hitting the ball better than at any point this season.
- The Dodgers star is batting .337/.394/.582 over the last 30 days. He has a 1.221 OPS in September.
- Betts has been crushing it against this line, topping it in seven of nine games this month and 18 of his last 30 contests.
Holliday to score (+120): This is a great price for a leadoff hitter who's ending the season strong.
Holliday is batting .355/.444/.581 in September, and he's gotten on base in 12 consecutive games.
He's scored eight runs over that stretch, including five of his last six contests.
Holliday and the Baltimore Orioles see Toronto Blue Jays right-hander Chris Bassitt, who has been great at home but has been hit much harder by lefty bats.
The Orioles' second baseman has contributed most of his production against righties.
- Vs. RHPs: .267/.340/.422, 13 HR
- Vs. LHPs: .213/.272/.327, 4 HR
Behind Bassitt is a Blue Jays bullpen that's 26th in ERA (5.17) since the all-star break.
MLB prop picks made at 1:40 p.m. ET on 09/12/2025.
