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The biggest pitching matchup of the day is happening in the afternoon, as Paul Skenes duels with Jacob Misiorowski.
Today's MLB props narrative: Both young guns can light up the radar gun, and Misiorowski should have a chance to mow down a Pirates lineup that often can't handle the heat. Later on Wednesday, the Seattle Mariners' offence looks to stay in a groove against Joe Ryan and the Minnesota Twins.
Check out the best MLB prop bets for June 25, featuring a prediction on Erick Fedde.
MLB prop bets
Best Bet: Julio Rodriguez over 0.5 runs (+128)
Rodriguez has been solid, but not spectacular, in recent games. But with how the Mariners are swinging the bats right now, he'll be a threat to score whenever he gets on.
Over the past two weeks, the Mariners rank second in MLB in wRC+ (142). Also, their strikeout rate in that span (20.1%) is notably lower than their season average (22.8%).
Rodriguez bats No. 2 for Seattle, right behind the MVP-calibre bat of Cal Raleigh. MLB's home run leader has homered in five of his past six games and has a 1.151 OPS this month.
With that in mind, you might think I'd just back Raleigh over 1.5 total bases (+102). I don't mind that play at all, but I'm more compelled by Rodriguez's price to score.
Rodriguez is 9-7 vs. this prop in his past 16 games, with a respectable .754 OPS in that span.
Seattle is 18-for-45 against Minnesota's Ryan with eight extra-base hits (.733 SLG). And Rodriguez has had his fair share of that success.
Key stat: Rodriguez is 4-for-9 with a home run, two doubles and a walk (1.500 OPS) vs. Ryan.
Best MLB picks
Misiorowski over 5.5 strikeouts (-132): As a 6-foot-7, 197-pound pitcher who hucks upper-90s fastballs, Misiorowski is kind of like a slightly bigger Jacob deGrom with less control.
The Brewers' rookie sits 99-plus with his four-seamer, and even his changeup can come in as high as 94 mph.
Stuff like that is difficult to control, but the results have also been electric.
Through two starts (11.0 innings), Misiorowski has allowed one hit and five walks while striking out 11 batters.
Despite how hard his pitches are coming in, the contact going out has been weak, as he's garnered a 27.3% hard-hit rate (MLB average is 41.0%), per Baseball Savant.
The Pittsburgh Pirates haven't seen Misiorowski yet, and I expect them to struggle. They have the sixth-highest strikeout rate in the majors (23.6%).
Pittsburgh also has the sixth-highest K rate on fastballs that are 99 mph or faster (41.5%).
Fedde over 17.5 outs (-114): Fedde is averaging 16.8 outs per game this season, so he's not quite at this mark in a typical outing. But he often gets oh so close.
The St. Louis right-hander has pitched into the sixth inning or deeper in 13 of 15 starts. So he's almost always given the opportunity to cash this bet.
I'm not scared of the Cubs' offence right now, given that the lineup has just a 99 wRC+ over the past 30 days.
Fedde's biggest issue is walks, but the Cubs have just a 6.9% walk rate in the past month (26th in MLB). Hopefully that impatience persists tonight.
The Cardinals deploy a six-man rotation, which puts more strain on the starters to give length. After using four relievers for 15-plus pitches last night — including the two highest-leverage guys — St. Louis would love to see Fedde eat some innings.
MLB prop picks made at 10:03 a.m. ET on 06/25/2025.
