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NFL Week 2 schedule, odds and betting lines: Matchups and top storylines

Patrick Mahomes and the Kansas City Chiefs battle the Philadelphia Eagles. Photo by Reed Hoffmann/AP,
Patrick Mahomes and the Kansas City Chiefs battle the Philadelphia Eagles. Photo by Reed Hoffmann/AP,

Week 1 delivered plenty of excitement for fans and bettors, and now the stage is set for an excellent NFL Week 2.

The latest: The Philadelphia Eagles started their title defence with a win over the Dallas Cowboys. Now, they hit the road to battle the Kansas City Chiefs in a Super Bowl rematch. Elsewhere, the week closes out with a Monday Night Football doubleheader.

Check out the latest NFL Week 2 schedule and betting lines below.

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NFL Week 2 schedule notes

  • The Eagles took care of business to open the NFL season, besting the Cowboys 24-20. They battle a Chiefs squad that's coming off a divisional loss to the Los Angeles Chargers. Star wide receiver Xavier Worthy was injured early in the contest. If he's out for Week 2, Kansas City will enter with a thin wide receiver room.
  • The Miami Dolphins are reeling after a terrible showing against the Indianapolis Colts. Tua Tagovailoa struggled, Jaylen Waddle exited with an injury (and returned), and Tyreek Hill was visibly frustrated on the sideline. They now host the New England Patriots.
  • All eyes will be on the Los Angeles Chargers again in Week 2. After beating the Chiefs in primetime, they visit the Las Vegas Raiders. Las Vegas is coming off a road win against the New England Patriots in Geno Smith's debut at quarterback.
  • Daniel Jones had one of the marquee performances of Week 1. The Indianapolis Colts quarterback threw for 272 yards and a touchdown while adding 26 yards and two scores on the ground. They'll face a bit of a tougher test in Week 2 against the Denver Broncos.
  • The Pittsburgh Steelers won an entertaining battle, 34-32, against the New York Jets. Aaron Rodgers looked good in his debut, throwing for 244 yards and four touchdowns in the victory. Now, they host the Seattle Seahawks in Week 2.
  • Josh Allen authored an epic comeback against the Baltimore Ravens, and now he hits the road for a divisional battle against the Jets. Buffalo is 0-3 ATS and 1-2 SU in its last two games at MetLife Stadium.

NFL Week 2 matchups: Thursday night

Washington Commanders vs. Green Bay Packers

Sunday's 1 p.m. slate

Buffalo Bills vs. New York Jets

Chicago Bears vs. Detroit Lions

Cleveland Browns vs. Baltimore Ravens

Jacksonville Jaguars vs. Cincinnati Bengals

Los Angeles Rams vs. Tennessee Titans

New England Patriots vs. Miami Dolphins

New York Giants vs. Dallas Cowboys

San Francisco 49ers vs. New Orleans Saints

Seattle Seahawks vs. Pittsburgh Steelers

Sunday's 4 p.m. slate

Carolina Panthers vs. Arizona Cardinals

Denver Broncos vs. Indianapolis Colts

Philadelphia Eagles vs. Kansas City Chiefs

Sunday & Monday Night Football matchups

Atlanta Falcons vs. Minnesota Vikings

Tampa Bay Buccaneers vs. Houston Texans

Los Angeles Chargers vs. Las Vegas Raiders

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